Profondo will make his Melbourne debut when he tackles the Australian Guineas at Flemington on Saturday.
Trainer Richard Litt has admitted he would have preferred to stay in Sydney with the colt, who is currently 18/5 for the feature race, but also feels that there are more positives than negatives for the son of Deep Impact.
Litt did not want to run the three-year-old on Randwick's heavy track, with Sydney enduring weeks of rainfall.
The three-year-old has now drawn barrier 15 in Saturday's Group 1 feature over 1600 metres and Litt is confident that everything is in place for his charge to shine, with all the action on the Sports Live Streaming platform.
"He's a pretty sensible horse and I don't think racing left-handed will be a problem," Litt said.
"I think it might be a bit of a positive on Saturday as he likes to lug-in a little bit in his races, so coming down here he will get on his other leg, and it might suit him."
The $1.9 million yearling purchase will again be ridden by Robbie Dolan and Litt says the colt was bouncing when he arrived in Flemington in the early hours of Friday morning.
"He came off the truck bouncing," Litt said. "Everything has to go his way on Saturday but he's very versatile. I don't want him jammed up on the fence looking for runs in the last 400 metres so that's why the barrier suits.
"Out there that's Robbie's (Dolan) deal, I can't have that pressure of riding him as well."