Will the Philadelphia Eagles stay perfect when they take on division rivals Dallas in Week 6, or can the Buffalo Bills avenge last January's loss at Arrowhead Stadium?
These questions and more will be answered on another superb slate of NFL games on Sunday as the Atlanta Falcons bid to upset the NFC West-leading San Francisco 49ers in one of the early matchups.
|What||San Francisco 49ers @ Atlanta Falcons|
|Where||Mercedes-Benz Stadium, Atlanta|
|When||1pm ET/10am PT Sunday, October 16th|
|How to watch||Fox, Streaming via fuboTV|
|Odds||SF 49ers -225, ATL Falcons +185|
The Falcons were expected to struggle in their first post-Matt Ryan season and with few playmakers on the roster, but Atlanta have been surprisingly competent through five weeks of football.
They are 2-3 and all five games have been decided by one score - so no blowouts, while they have also demonstrated an ability to come through in a couple of close ones.
And they are probably catching the visiting 49ers at a good time here with San Francisco coming off a big win over the Carolina Panthers to play their second successive early game on the East Coast.
Injuries are mounting up for Kyle Shanahan's men with star pass rusher Nick Bosa the latest to go down, following the losses of QB Trey Lance and LT Trent Williams earlier this season.
Bosa is questionable to play and his absence could be huge for the NFL's leading defense, which is already without their two best defensive tackles and a starting cornerback.
The Falcons are 5-0 ATS and can keep the banged-up Niners within reach to cover the +5.5 point Spread at -110. The return of star tight end Kyle Pitts from injury to boost their passing game will be particularly helpful.
|What||Buffalo Bills @ Kansas City Chiefs|
|Where||Arrowhead Stadium, Kansas City|
|When||4.25pm ET/1.25pm PT Sunday, October 16th|
|How to watch||CBS, Streaming via Paramount+|
|Odds||BUF Bills -145, KC Chiefs +125|
This is the matchup the Bills have been waiting for ever since last January's heartbreaking overtime loss to the Chiefs ended their Super Bowl tilt.
It's at Arrowhead Stadium again, which is never an easy place to win, but Buffalo's stacked roster come in as favorites to take down the Chiefs this time.
Kansas City QB Patrick Mahomes is an underdog at home for the first time ever as a starter and, given his level of play and the telepathic connection he enjoys with Travis Kelce, it is surely too tempting not to take the Chiefs with the points.
Kansas City have won three of the last four meetings with the Bills, including the AFC divisional round shootout where 13 seconds was enough time on the clock for Mahomes to work his magic.
Buffalo are 1-3 against the spread in those meetings and may not cover the -2.5 point Spread with the hosts looking like the better play at -110 receiving just less than a field goal.
|What||Dallas Cowboys @ Philadelphia Eagles|
|Where||Lincoln Financial Field, Philadelphia|
|When||8.20pm ET/5.20pm PT Sunday, October 16th|
|How to watch||NBC, Streaming via fuboTV+|
|Odds||DAL Cowboys +220, PHI Eagles -270|
It's starting to feel like the Philadelphia Eagles could be about to do something special again.
The NFL's last remaining unbeaten team face their greatest test of 2022 so far from NFC East rivals the Dallas Cowboys in Sunday's prime-time matchup.
Eagles QB Jalen Hurts, a surprise MVP candidate if he can keep up his current level of production, is thriving in Philly's RPO-heavy offense.
His ability to scramble will be tested this week by a dominant Cowboys pass rush that goes up against a weakened Eagles offensive line, but the home team will fancy their chances of knocking Dallas backup QB Cooper Rush out of his stride.
The Rush Cinderella story has been great for four weeks, but he has not faced a defense as good as the Eagles unit - which is currently ranked fourth overall and fifth against the pass.
The crowd can be a factor too with Philadelphia sports fans in the midst of the wildest weekend in over a decade and likely to provide a raucous atmosphere for the players to feed off.
Hurts, who has won eight consecutive regular-season games, converted six QB sneaks against the Cardinals and could be a major end zone threat himself here at +110 as an anytime TD scorer.